IJHS
Interprofessional Journal of Health Sciences
formerly Bulletin of Health, Science and Technology (BHST)
https://ijhs.rsu.ac.th
ISSN (Print) 2672-9628
ISSN (Online) 2672-9423
Interprofessional Journal of Health Sciences. Vol.18 No.2 , July - December 2020.
PHARMACOGNOSTIC EVALUATION OF PELTOPHORUM DASYRRACHIS (MIQ.) KURZ BARK
Kanyarat Peng-ngummuang, Jintana Junlatat, Puntiwa Krachai, Jakrapong Thangthong, Nusara Pernjit, and Sudjai Yaphet
Abstract
This study is preliminary evaluation of pharmacognostic parameters of Peltophorum dasyrrachis (Miq.) KURZ bark. P. dasyrrachis belongs to Fabaceae family and is traditionally used in the treatment of diabetic ulcers. Three authentic samples that are regularly used for treatment were identified and collected by a folk healer, Mr. Kitti Nakhun, who has expertise in treating diabetic wounds using herbs in Ubon Ratchathani province. Macroscopic and microscopic characteristics of the crude drugs were illustrated. The plant part used was obtained from the dried brownish bark. Observation under the microscope found that this plant presented starch granules, calcium oxalate, prism crystal and reddish pigment. In addition, the physicochemical properties including foreign matter, loss on drying, total ash, acid-insoluble ash, water soluble extractive, ethanol soluble extractives were 0.96±0.09, 1.64 ± 0.56, 5.78 ± 0.20, 0.40 ± 0.31, 16.62 ± 1.07 and 22.20 ± 0.44 % w/w, respectively. Moreover, the high-performance liquid chromatography (HPLC) analysis exhibited a HPLC-profile and contained wound healing and improving substances; gallic acid and vanillin in a concentration range of 1.87 - 1.91 and 0.38 - 0.40 mg/g, respectively. This study provided scientific evidence for authentic identification, and quality control of P. dasyrrachis crude drugs.
Keywords: Peltophorum dasyrrachis, Pharmacognostic evaluation, HPLC-profile